ITGA2B Antibody

Blue Ice

Observed: 135kDa

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.

None

Mouse liver

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Recombinant fusion protein containing a sequence corresponding to amino acids 693-993 of human ITGA2B (NP_000410.2).

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Optimal dilutions for each application to be determined by the researcher.