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PRPF8 Antibody

PRPF8 Antibody

Item no.	PRS-19-988-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	PRPF8
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 274kDa
Manufacturer - Research Area	Neuroscience
Background	Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
By Type	Neuroscience
Modifications	None
Purification	Affinity purification
Positive Control 1	HeLa
Positive Control 2	Jurkat
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:1000 IHC: 1:50 - 1:100 IF: 1:50 - 1:100 IP: 1:50 - 1:100
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRPF8 (NP_006436.3).
Clonality	Polyclonal
NCBI Official Name	pre-mRNA processing factor 8
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names	HPRP8, PRP8, PRPC8, RP13, SNRNP22pre-mRNA-processing-splicing factor 8, 220 kDa U5 snRNP-specific protein, PRP8 homolog, PRP8 pre-mRNA processing factor 8 homolog, U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p, apoptosis-regulated protein 1, apoptosis-regulated protein 2, p22precursor mRNA processing protein, splicing factor Prp8

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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