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PDE5A Antibody

PDE5A Antibody

Item no.	PRS-22-501-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Antibodies Western Blot Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	PDE5A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PDE5A,CN5A,PDE5,PDE5A1,CGB-PDE,phosphodiesterase 5A,cGMP-specific,cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 100kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Signal Transduction
Background	This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
By Type	Cancer, Cell Cycle, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	HT-1080
Positive Control 2	SKOV3
Positive Control 3	A-549
Positive Control 4	22Rv1
Positive Control 5	Mouse brain
Positive Control 6	Mouse skeletal muscle
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDE5A (NP_001074.2).
Clonality	Polyclonal
NCBI Official Name	phosphodiesterase 5A, cGMP-specific
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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