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USP8 Antibody

USP8 Antibody

Item no.	PRS-22-643-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Antibodies Cell Biology Cell Status Western Blot Immunofluorescence Autophagy Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	USP8
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ubiquitin carboxyl-terminal hydrolase 8,Deubiquitinating enzyme 8,Ubiquitin isopeptidase Y,hUBPy,Ubiquitin thioesterase 8,Ubiquitin-specific-processing protease 8,USP8,KIAA0055,UBPY
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 131kDa
Manufacturer - Research Area	Cell Cycle
Background	This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.
By Type	Cell Cycle
Modifications	None
Purification	Affinity purification
Positive Control 1	MCF7
Positive Control 2	THP-1
Positive Control 3	A-549
Positive Control 4	H125
Positive Control 5	Mouse brain
Positive Control 6	Mouse lung
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human USP8 (NP_005145.3).
Clonality	Polyclonal
NCBI Official Name	Ubiquitin carboxyl-terminal hydrolase 8
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 12/4/2025

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