Comparison

NBR1 Antibody

Item no. PRS-23-029-100uL
Manufacturer ProSci
Amount 100 uL
Quantity options 100 uL
Category
Type Antibody Primary
Format Liquid
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
NCBI NBR1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 1A1-3B,IAI3B,M17S2,MIG19,next to BRCA1 gene 1 protein,B-box protein,cell migration-inducing gene 19 protein,membrane component,chromosome 17,surface marker 2 (ovarian carcinoma antigen CA125),migration-inducing protein 19,neighbor of BRCA1 gene 1
Shipping Condition Cool pack
Available
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 110kDa
Manufacturer - Research Area
Autophagy, Cell Cycle
Background
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
By Type
Autophagy, Cell Cycle
Modifications
None
Purification
Affinity purification
Positive Control 1
SKOV3
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NBR1 (NP_005890.2).
Clonality
Polyclonal
NCBI Official Name
NBR1 autophagy cargo receptor
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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