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L1CAM Antibody, KO Validated

L1CAM Antibody, KO Validated

Item no.	PRS-23-656-100uL
Manufacturer	ProSci
Amount	100 uL
Quantity options	100 uL
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Neural Development Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cytoskeleton Western Blot Primary Antibodies By Organ Lung Cancer small GTPases Ras Subfamily
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
NCBI	L1CAM
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Neural cell adhesion molecule L1,N-CAM-L1,NCAM-L1,CD171,L1CAM,CAML1,MIC5
Shipping Condition	Cool pack
Available
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 200kDa
Manufacturer - Research Area	Cell Cycle, Immunology, Neuroscience, Signal Transduction
Background	The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
By Type	Cell Cycle, Immunology, Neuroscience, Signal Transduction
Badges	KO
Modifications	None
Purification	Affinity purification
Validation	Antibody is Knockout validated.
Positive Control 1	SH-SY5Y
Positive Control 2	Mouse brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1143-1257 of human L1CAM (NP_000416.1).
Clonality	Polyclonal
NCBI Official Name	Neural cell adhesion molecule L1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Validation	Antibody is Knockout validated.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 11/6/2025

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