Anti-Butyryl-Histone H3 (Lys14) Rabbit mAb

Histone & Histone Modification Antibodies

Store at -20°C. Avoid freeze/thaw cycles.

Epigenetics

Protein A purified

PBS, Glycerol, BSA

Lys14

Recombinant Monoclonal

H3 is core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histones are subjected to a variety of enzyme catalyzed modifications, including acetylation, methylation, phosphorylation, ubiquitylation, etc. Butyrylation of histones marks active promoters and competes with histone acetylation, which occurs during late