ADRB2 (Beta-2 Adrenergic Receptor, Beta-2 Adrenoreceptor, Beta-2 Adrenoceptor, ADRB2R, B2AR)

Antibodies / Antibodies-Receptors

-20°C

Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.

Synthetic peptide corresponding to the Internal region of human AR-beta2.

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Applications:
Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunofluorescence: 1:200-1:1000
ELISA: 1:20, 000
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.