HNRPK (Heterogeneous Nuclear Ribonucleoprotein K, Transformation Up-regulated Nuclear Protein, hnRNP K, TUNP, HNRNPK)

Antibodies / Antibodies-RNA Processing

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Synthetic peptide SVKQYSGKFF conjugated to Ovalbumin.

hnRNP K (Heterogeneous nuclear ribonucleoprotein K) is a pre-mRNA binding protein and a component of hnRNP complexes providing substrate for pre-mRNA processing before becoming translatable mRNAs in cytoplasm. This protein containing KH domains and is ubiquitously expressed in the cytoplasm and the nucleus with a predicted molecular weight approximately 51kD. hnRNP K expression and function are increased by epidermal growth factor (EGF). hnRNP K acts as transcriptional regulator and functions in nucleocytoplasmic shuttling, and is modified by phosphorylation (PKC delta, c-Src) and acetylation.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.