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Goat Anti-Catalase / CAT Antibody

Goat Anti-Catalase / CAT Antibody

Item no.	ABC-AF1195a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC, ELISA
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CAT, Catalase, 1.11.1.6
Available
Primary Accession	P04040
Antigen Type	Synthetic Peptide
Application	WB, IHC, E
Bio Background	This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Bio References	The association of -262C/T polymorphism in the catalase gene and delayed graft function of kidney allografts. Dutkiewicz G, et al. Nephrology (Carlton), 2010 Aug. PMID 20649881. Epistasis of oxidative stress-related enzyme genes on modulating the risks in oral cavity cancer. Wu SH, et al. Clin Chim Acta, 2010 Nov 11. PMID 20643115. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Promoter Variant in the Catalase Gene Is Associated with Vitiligo in Chinese People. Liu L, et al. J Invest Dermatol, 2010 Jul 8. PMID 20613769. [Effects of catalase gene (RS769217) polymorphism on energy homeostasis and bone status are gender specific] Vitai M, et al. Orv Hetil, 2010 Jun 6. PMID 20494887.
Clonality	Polyclonal
Gene ID	847
Gene Name	CAT
Subtitle	Peptide-affinity purified goat antibody
Reactivity	H, M, Rat
Legend image 1	AF1195a (2 µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Type image 1	IHC
Legend image 2	AF1195a (1 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 2	WB
Other Accession	NP_001743; 847; 12359 (mouse);
Predicted	Dog
Concentration (mg/ml)	0.5mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/4/2025

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