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SMO / Smoothened Antibody (clone 3D10)

SMO / Smoothened Antibody (clone 3D10)

Item no.	ABC-ALS14524
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Applications	WB, ELISA, IHC-P
Clone	3D10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG3
Citations	Stone D.M.,et al.Nature 384:129-134(1996). Xie J.,et al.Nature 391:90-92(1998). Jiang N.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases. Scherer S.W.,et al.Science 300:767-772(2003). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Smoothened homolog, SMO, Protein Gx, SMO, SMOH
Similar products	SMO, SMOH, Smoothened homolog, Protein Gx
Available
Manufacturer - Targets	Human SMO / Smoothened
Storage Conditions	Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Bio Background	G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
Clonality	Monoclonal
Gene Name	SMO
Subtitle	Mouse Monoclonal Antibody
Reactivity	H
Calculated Molecular Weight	86397
Purification	Protein A purified
Concentration	0.48 mg/ml
Dilution	IHC-P (5 µg/ml)
Antigen Type	Recombinant protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 11/6/2025

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