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ATG16L1 Antibody

ATG16L1 Antibody

Item no.	ABC-AM1817b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IHC-P
Clone	54CT27.2.6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. Metzger S, et al. Hum Genet, 2010 Oct. PMID 20697744. Plasma membrane contributes to the formation of pre-autophagosomal structures. Ravikumar B, et al. Nat Cell Biol, 2010 Aug. PMID 20639872. Replication and meta-analysis of 13,000 cases defines the risk for interleukin-23 receptor and autophagy-related 16-like 1 variants in Crohn's disease. Cotterill L, et al. Can J Gastroenterol, 2010 May. PMID 20485703. Is there a role for Crohn's disease-associated autophagy genes ATG16L1 and IRGM in formation of granulomas? Wolfkamp SC, et al. Eur J Gastroenterol Hepatol, 2010 Aug. PMID 20395867. NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease. Gazouli M, et al. World J Gastroenterol, 2010 Apr 14. PMID 20380008.
NCBI	NP_001177195.1,NP_001177196.1,NP_060444.3,NP_110430.5,NP_942593.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Autophagy-related protein 16-1,APG16-like 1,ATG16L1,APG16L
Similar products	ATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Cell Biology; Metabolism; Neuroscience; Autophagy; Autophagy; Regulation of autophagy
Manufacturer - Targets	Purified His-tagged ATG16L1 protein(Fragment) was used to produced this monoclonal antibody.
Bio Background	The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 1 (IBD1). Several transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	ATG16L1 {ECO:0000303\|PubMed:17200669, ECO:0000312\|HGNC:HGNC:21498}
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	68265
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	WB: 1:60 IHC-P: 1:10~50

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 1/1/2026

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