Comparison

GAD2 Antibody (Ascites)

Item no. ABC-AM2049a
Manufacturer Abcepta
Amount 100 ul
Category
Type Antibody Monoclonal
Applications WB
Clone 458CT17.2.4
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010):
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010):
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
NCBI NP_000809.1,NP_001127838.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Glutamate decarboxylase 2,65 kDa glutamic acid decarboxylase,GAD-65,Glutamate decarboxylase 65 kDa isoform,GAD2,GAD65
Similar products GAD-65, GAD2, GAD65, Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, Glutamate decarboxylase 65 kDa isoform
Available
Manufacturer - Category
Primary Antibodies; Metabolism; Neuroscience
Manufacturer - Targets
This GAD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from human GAD2.
Bio Background
This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantibody and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Alternative splicing results in multiple transcript variants thatencode the same protein.
Clonality
Monoclonal
Gene Name
GAD2
Subtitle
Mouse Monoclonal Antibody (Mab)
Reactivity
H, Rat
Predicted Reactivity
M, Pig
Calculated Molecular Weight
65411
Antigen Source
HUMAN
Antigen Region
109-138
Formulation
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Dilution
WB: 1:100~1600
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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