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GC Antibody(Center) (Ascites)

GC Antibody(Center) (Ascites)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Isotype	IgM
Format	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Applications	WB
Amount	100 ul
Host	Mouse
Item no.	ABC-AM2180a
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P04062
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Bio References	Dos Santos, A.V., et al. Neurosci. Lett. 485(2):121-124(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jeong, S.Y., et al. Blood Cells Mol. Dis. (2010) In press : Hu, F.Y., et al. Eur. J. Neurol. (2010) In press : Velayati, A., et al. Curr Neurol Neurosci Rep 10(3):190-198(2010)
Clonality	Monoclonal
Clone/Animal Names	660CT8.6.6.2
Gene ID	2629
Gene Name	GBA (HGNC:4177)
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Legend image 1	GC Antibody(Center) (Cat. #AM2180a) western blot analysis in MCF-7 cell line lysates (35μg/lane).This demonstrates the GC antibody detected the GC protein (arrow).
Type image 1	WB
Dilution image 1	1:100~1600
Other Accession	Q70KH2; Q2KHZ8; NP_000148.2
Predicted	B, Pig
Isotype	IgM
Calculated MW	59716
Antigen Region	337-365
Antigen Source	HUMAN
Target/Specificity	This GC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
NCBI Accession	NP_000148.2; NP_001005741.1; NP_001005742.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-AM2180a-datasheet.pdf

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Amount: 100 ul

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Delivery expected until 7/4/2024