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PARK8 (LRRK2) Antibody

PARK8 (LRRK2) Antibody

Item no.	ABC-AM7099a
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IHC-P
Clone	133AT1218
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Citations	Olfactory heterogeneity in LRRK2 related Parkinsonism. Silveira-Moriyama L, et al. Mov Disord, 2010 Sep 3. PMID 20818658. LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease. Saunders-Pullman R, et al. Mov Disord, 2010 Sep 3. PMID 20818610. Low frequency of common LRRK2 mutations in Mexican patients with Parkinson's disease. Yescas P, et al. Neurosci Lett, 2010 Aug 18. PMID 20727385. Absence of Commonly Reported Leucine-Rich Repeat Kinase 2 Mutations in Eastern Indian Parkinson's Disease Patients. Sanyal J, et al. Genet Test Mol Biomarkers, 2010 Aug 19. PMID 20722494. Penetrance in Parkinson's disease related to the LRRK2 R1441G mutation in the Basque country (Spain). Ruiz-Martínez J, et al. Mov Disord, 2010 Aug 18. PMID 20721916.
NCBI	NP_940980.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Leucine-rich repeat serine/threonine-protein kinase 2,Dardarin,LRRK2,PARK8
Similar products	LRRK2, PARK8, Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Neuroscience; Autophagy; Lysosome; Mitochondrion; Mitochondrion outer membrane
Manufacturer - Targets	This PARK8 (LRRK2) antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.
Bio Background	This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD4 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Clonality	Monoclonal
Gene Name	LRRK2
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H, M
Calculated Molecular Weight	286103
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	IHC: 1:50 WB: 1:100~500 WB: 1:2000

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 2/5/2026

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