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DDR1 Antibody

DDR1 Antibody

Item no.	ABC-AM8458b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neural Lineage Markers Neural Signaling Neural Adhesion Molecules Antibodies Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Immunohistochemistry Western Blot Primary Antibodies Astrocytoma Colorectal Cancer Interneuron Markers
Type	Antibody Monoclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Mouse
Isotype	IgG2b kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, Mammary carcinoma kinase 10, MCK-10, Protein-tyrosine kinase 3A,
Available
Primary Accession	Q08345
Bio Background	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Bio References	di Marco E., et al.J. Biol. Chem. 268:24290-24295(1993). Johnson J.D., et al.Proc. Natl. Acad. Sci. U.S.A. 90:5677-5681(1993). Laval S., et al.Cell Growth Differ. 5:1173-1183(1994). Perez J.L., et al.Oncogene 9:211-219(1994). Sakuma S., et al.FEBS Lett. 398:165-169(1996).
Gene ID	780
Gene Name	DDR1
Reactivity	H
Calculated MW	101128
Antigen Source	HUMAN
Target/Specificity	This DDR1 antibody is generated from a mouse immunized with a recombinant protein.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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