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IRF1 Antibody (Center)

IRF1 Antibody (Center)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	ABC-AP11860c
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P10914
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Bio References	Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010) Matsuzaki, S., et al. J. Immunol. 185(8):4863-4872(2010) Antonios, D., et al. J. Immunol. 185(1):89-98(2010) Lou, Y.J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(3):255-258(2010) Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Clonality	Polyclonal
Clone/Animal Names	RB31743
Gene ID	3659
Gene Name	IRF1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	IRF1 Antibody (Center) (Cat. #AP11860c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the IRF1 antibody detected the IRF1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P23570; A0FIN4; P15314; Q3SZP0; NP_002189.1
Predicted	B, M, Pig, Rat
Isotype	Rabbit Ig
Calculated MW	36502
Antigen Region	74-102
Antigen Source	HUMAN
Target/Specificity	This IRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the Central region of human IRF1.
NCBI Accession	NP_002189.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-AP11860c-datasheet.pdf

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Amount: 400 ul

available

Delivery expected until 6/6/2024