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RIPK1 Antibody (N-term)

RIPK1 Antibody (N-term)

Item no.	ABC-AP13893a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Kim, S., et al. Cancer Sci. 101(11):2425-2429(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Chae, Y.S., et al. J. Cancer Res. Clin. Oncol. (2010) In press: Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):251-257(2010) Vandenabeele, P., et al. Sci Signal 3 (115), RE4 (2010) :
NCBI	NP_003795.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Receptor-interacting serine/threonine-protein kinase 1,Cell death protein RIP,Receptor-interacting protein 1,RIP-1,Serine/threonine-protein kinase RIP,RIPK1,RIP,RIP1
Similar products	RIPK1, RIP, RIP1, Receptor-interacting serine/threonine-protein kinase 1, Cell death protein RIP, Receptor-interacting protein 1, Serine/threonine-protein kinase RIP, RIP-1
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Signal Transduction; RIG-l-like Receptor; Toll-Like receptor signaling; SARS druggable targets; SARS CoV2 PPIs; Ub protein ligase binding; Apoptosis; Apoptosis signaling; Necroptosis; Necrosis
Manufacturer - Targets	This RIPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the N-terminal region of human RIPK1.
Bio Background	Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB34026
Gene Name	RIPK1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	75931
Antigen Source	HUMAN
Antigen Region	152-180
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 1/1/2026

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