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BIRC2 Antibody (Center)

BIRC2 Antibody (Center)

Item no.	ABC-AP14418c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Hinz, M., et al. Mol. Cell 40(1):63-74(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Meng, N., et al. J. Cell. Physiol. 225(1):174-179(2010) Burke, S.P., et al. J. Biol. Chem. 285(39):30061-30068(2010) Mace, P.D., et al. J. Mol. Biol. 400(1):8-15(2010)
NCBI	NP_001157.1,NP_001243092.1,NP_001243095.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Baculoviral IAP repeat-containing protein 2,632-,C-IAP1,IAP homolog B,Inhibitor of apoptosis protein 2,IAP-2,hIAP-2,hIAP2,RING finger protein 48,TNFR2-TRAF-signaling complex protein 2,BIRC2,API1,IAP2,MIHB,RNF48
Similar products	BIRC2, API1, IAP2, MIHB, RNF48, Baculoviral IAP repeat-containing protein 2, C-IAP1, IAP homolog B, Inhibitor of apoptosis protein 2, RING finger protein 48, TNFR2-TRAF-signaling complex protein 2, IAP-2, 632-, hIAP-2, hIAP2
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Metabolism; Signal Transduction; Ubiquitin E3 Ligases (RING Domain) Antibodies; Apoptosis; Apoptosis signaling
Manufacturer - Targets	This BIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the Central region of human BIRC2.
Bio Background	The protein encoded by this gene is a member of a familyof proteins that inhibits apoptosis by binding to tumor necrosisfactor receptor-associated factors TRAF1 and TRAF2, probably byinterfering with activation of ICE-like proteases. This encodedprotein inhibits apoptosis induced by serum deprivation andmenadione, a potent inducer of free radicals.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB34387
Gene Name	BIRC2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M
Calculated Molecular Weight	69900
Antigen Source	HUMAN
Antigen Region	216-244
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 1/1/2026

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