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APC Antibody (Center)

APC Antibody (Center)

Item no.	ABC-AP19274c
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Western Blot Primary Antibodies By Organ Colorectal Cancer
Type	Antibody Polyclonal
Applications	WB
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Chung, K.H., et al. J Neurosurg Pediatr 6(4):372-376(2010) Rai, K., et al. Cell 142(6):930-942(2010) Poulogiannis, G., et al. Proc. Natl. Acad. Sci. U.S.A. 107(34):15145-15150(2010) Jaulin, F., et al. J. Cell Biol. 190(3):443-460(2010) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
NCBI	NP_000029.2,NP_001120982.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Adenomatous polyposis coli protein,Protein APC,Deleted in polyposis 25,APC,DP25
Similar products	APC, Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 25, DP25
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies
Manufacturer - Targets	This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
Bio Background	This gene encodes a tumor suppressor protein that acts asan antagonist of the Wnt signaling pathway. It is also involved inother processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this genecause familial adenomatous polyposis (FAP), an autosomal dominantpre-malignant disease that usually progresses to malignancy.Disease-associated mutations tend to be clustered in a small regiondesignated the mutation cluster region (MCR) and result in atruncated protein product.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB37442
Gene Name	APC
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Calculated Molecular Weight	311646
Antigen Source	HUMAN
Antigen Region	1148-1176
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 3/5/2026

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