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FANCL Antibody(C-term)

FANCL Antibody(C-term)

Manufacturer	Abcepta
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Western Blot Autophagy Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Isotype	Ig
Applications	Western Blot
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP19508b-ev-80ul
Targets	FANCL;;RAD51C;;UBE2K
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	Q9NW38
Other Accession	NP_001108108.1
Antigen Type	Synthetic Peptide
Bio Background	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
Bio References	Zhang, J., et al. J. Clin. Invest. 120(5):1524-1534(2010) Garcia, M.J., et al. Carcinogenesis 30(11):1898-1902(2009) McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(9):2549-2552(2009) Longerich, S., et al. J. Biol. Chem. 284(35):23182-23186(2009) Hess, C.J., et al. Cell. Oncol. 30(4):299-306(2008)
Gene ID	55120
Gene Name	FANCL
Reactivity	H
Calculated MW	42905
Antigen Region	274-302
Antigen Source	HUMAN
Target/Specificity	This FANCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the C-terminal region of human FANCL.
NCBI Accession	NP_001108108.1; NP_060532.2

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Amount: 80 ul

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