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IL28RA Antibody (Center)

IL28RA Antibody (Center)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP21372c-ev
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	Q8IU57
Application	WB
Bio Background	The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus- activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
Bio References	Dumoutier L., et al.Biochem. J. 370:391-396(2003). Sheppard P., et al.Nat. Immunol. 4:63-68(2003). Kotenko S.V., et al.Nat. Immunol. 4:69-77(2003). Ota T., et al.Nat. Genet. 36:40-45(2004). Gregory S.G., et al.Nature 441:315-321(2006).
Clonality	polyclonal
Clone/Animal Names	RB47814
Gene ID	163702
Gene Name	IFNLR1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-IL28RA Antibody (Center)at 1:2000 dilution + Ramos whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Isotype	Rabbit Ig
Calculated MW	57653
Antigen Source	HUMAN
Target/Specificity	This IL28RA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 387-420 amino acids from the Central region of human IL28RA.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-AP21372c-ev-datasheet.pdf

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Amount: 80 ul

available

Delivery expected until 6/6/2024