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U2AF1 Antibody (Center S70)

U2AF1 Antibody (Center S70)

Item no.	ABC-AP2802c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	U2AF1, U2AF35, U2AFBP, U2 snRNP auxiliary factor small subunit, Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1
Available
Primary Accession	Q01081
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	U2AF1 belongs to the splicing factor SR family. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers.
Bio References	Rino, J., Mol. Cell. Biol. 28 (9), 3045-3057 (2008) Little, J.T., J. Biol. Chem. 283 (13), 8145-8152 (2008) Pacheco, T.R., Mol. Cell. Biol. 26 (21), 8183-8190 (2006)
Clonality	Polyclonal
Clone/Animal Names	RB17371
Gene ID	102724594; 7307
Gene Name	U2AF1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-U2AF1 Antibody (Center S70) (Cat.#AP2802c) in Ramos cell line lysates (35ug/lane).U2AF1(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of U2AF1 (arrow) using rabbit polyclonal U2AF1 Antibody (Center S70) (Cat.#AP2802c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the U2AF1 gene.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with U2AF1 antibody (Center S70), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	Q9D883; A1A4K8; P0DN76
Predicted	B, M
Isotype	Rabbit Ig
Calculated MW	27872
Antigen Region	55-83
Antigen Source	HUMAN
Target/Specificity	This U2AF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human U2AF1.
NCBI Accession	NP_001020374.1; NP_001020375.1; NP_006749.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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