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Bi-Phospho-MEK1(S218/222) Antibody

Bi-Phospho-MEK1(S218/222) Antibody

Item no.	ABC-AP3159a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	WB, IHC-P, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Ohren, J.F., et al., J. Neural Transm. 11(12):1192-1197 (2004). Naegele, S., et al., J. Biol. Chem. 279(44):46023-46034 (2004). Ussar, S., et al., J. Biol. Chem. 279(42):43861-43869 (2004). Beausoleil, S.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135 (2004). Spence, H.J., et al., EMBO Rep. 5(5):484-489 (2004).
NCBI	NP_002746.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dual specificity mitogen-activated protein kinase kinase 1,MAP kinase kinase 1,MAPKK 1,MKK1,ERK activator kinase 1,MAPK/ERK kinase 1,MEK 1,MAP2K1,MEK1,PRKMK1
Similar products	MAP2K1, MEK1, Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAPK/ERK kinase 1, PRKMK1, MKK1, MAP kinase kinase 1, MAPKK 1, MEK 1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Developmental Biology; Signal Transduction; Phospho Antibodies; Anti-Kinome Antibodies; Toll receptor signaling; Toll-Like receptor signaling; B cell receptor signaling; Fc gamma R-mediated phagocytosis; T cell activation; T cell receptor signaling; Chemokine signaling
Manufacturer - Targets	This MEK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S218/222 of human MEK1.
Bio Background	MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB05985
Gene Name	MAP2K1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Dr, E, Ha, M, Rb, Rat, X, C
Calculated Molecular Weight	43439
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:500 IHC-P: 1:50~100 DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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