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Phospho-STAT1(S727) Antibody

Phospho-STAT1(S727) Antibody

Item no.	ABC-AP3256a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	STAT1, Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84
Available
Primary Accession	P42224
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.
Bio References	Garcin, D., et al., J. Virol. 78(16):8799-8811 (2004). Melen, K., et al., J. Med. Virol. 73(4):536-547 (2004). Klampfer, L., et al., J. Biol. Chem. 279(29):30358-30368 (2004). Marg, A., et al., J. Cell Biol. 165(6):823-833 (2004). Chim, C.S., et al., Blood 103(12):4630-4635 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB6033
Gene ID	6772
Gene Name	STAT1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-Phospho-STAT1 Pab (Cat. #AP3256a) in mouse brain tissue lysate (35ug/lane). Phospho-STAT1(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q764M5; P42225
Predicted	M, Pig
Isotype	Rabbit Ig
Calculated MW	87335
Antigen Source	HUMAN
Target/Specificity	This STAT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S727 of human STAT1.
NCBI Accession	NP_009330.1; NP_644671.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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