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FBXL2 Antibody (C-term)

FBXL2 Antibody (C-term)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IHC-P
Amount	400 ul
Host	Rabbit
Item no.	ABC-AP5030b
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	Q9UKC9
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats.
Bio References	Ye, J. PLoS Pathog. 3 (8), E108 (2007) Ilyin, G.P., et al. Genomics 67(1):40-47(2000) Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
Clonality	Polyclonal
Clone/Animal Names	RB30004
Gene ID	25827
Gene Name	FBXL2 (HGNC:13598)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-FBXL2 Antibody (C-term) at 1:1000-1:2000 dilution Lane 1: Human heart lysate Lane 2: Human liver lysate Lane 3: Hela whole cell lysate Lane 4: MDA-MB-453 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000-1:2000
Legend image 2	FBXL2 Antibody (C-term) (Cat. #AP5030b) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	FBXL2 Antibody (C-term) (Cat. #AP5030b) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	Q8BH16
Predicted	M
Isotype	Rabbit Ig
Calculated MW	47062
Antigen Region	366-395
Antigen Source	HUMAN
Target/Specificity	This FBXL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-395 amino acids from the C-terminal region of human FBXL2.
NCBI Accession	NP_001165184.1; NP_036289.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 7/4/2024