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GNAS Antibody (Center)

GNAS Antibody (Center)

Item no.	ABC-AP6865c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GNAS, Adenylate cyclase-stimulating G alpha protein, Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, Extra large alphas protein, XLalphas, GNAS1 {ECO:0000303\|PubMed:9707596}
Available
Primary Accession	Q5JWF2
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Bio References	Liu, C., et.al., Eur Arch Otorhinolaryngol (2009) Nishihara, E., et.al., Endocr. J. 56 (6), 791-798 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB17867
Gene ID	2778
Gene Name	GNAS
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-GNAS Antibody (Center) at 1:4000 dilution + Ramos whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 111 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:4000
Isotype	Rabbit Ig
Calculated MW	111025
Antigen Region	640-667
Antigen Source	HUMAN
Target/Specificity	This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-667 amino acids from the Central region of human GNAS.
NCBI Accession	NP_536350.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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