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Pyruvate Kinase (PKM2) Antibody (C-term)

Pyruvate Kinase (PKM2) Antibody (C-term)

Item no.	ABC-AP7044B
Manufacturer	Abcepta
Amount	200 ul
Category	Metabolism Glucose Homeostasis Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Isotype	IgG
Citations	References for protein: 1.Williams, J.M., et al., Mol. Microbiol. 27(1):171-186 (1998). 2.Gress, T.M., et al., Oncogene 13(8):1819-1830 (1996). 3.Kato, H., et al., Proc. Natl. Acad. Sci. U.S.A. 86(20):7861-7865 (1989). 4.Tsutsumi, H., et al., Genomics 2(1):86-89 (1988). 5.Tani, K., et al., Gene 73(2):509-516 (1988). References for MCF7 cell line: 1.Soule, HD; Vazquez J; Long A; Albert S; Brennan M. (1973). "A human cell line from a pleural effusion derived from a breast carcinoma". Journal of the National Cancer Institute 51 (5): 1409–1416. [PMID 4357757]. 2.Levenson, AS; Jordan VC. (1997). "MCF-7: the first hormone-responsive breast cancer cell line". Cancer Research 57 (15): 3071–3078. [PMID 9242427]. 3.Lacroix, M; Leclercq G. (2004). "Relevance of breast cancer cell lines as models for breast tumours: an update". Breast Research and Treatment 83 (3): 249–289.[PMID 14758095].
NCBI	NP_001193725.1,NP_001193726.1,NP_001193727.1,NP_001193728.1,NP_002645.3,NP_872270.1,NP_872271.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pyruvate kinase PKM,Cytosolic thyroid hormone-binding protein,CTHBP,Opa-interacting protein 3,OIP-3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Thyroid hormone-binding protein 1,THBP1,Tumor M2-PK,p58,PKM,OIP3,PK2,PK3,PKM2
Similar products	PKM2, PKM, OIP3, PK2, PK3, Cytosolic thyroid hormone-binding protein, Opa-interacting protein 3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, Tumor M2-PK, p58, CTHBP, THBP1, Pyruvate kinase PKM, OIP-3
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction; Catalog Updated
Manufacturer - Targets	This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).
Bio Background	There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB3697
Gene Name	PKM
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Pr, Rat
Calculated Molecular Weight	57937
Antigen Source	HUMAN
Antigen Region	476-505
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:200 WB: 1:1000 WB: 1:1000 WB: 1:2000 IHC-P: 1:50~1:100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 1/1/2026

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