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REA (PHB2) Antibody (N-term)

REA (PHB2) Antibody (N-term)

Item no.	ABC-AP7270a
Manufacturer	Abcepta
Amount	400 ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Takata,H., Curr. Biol. 17 (15), 1356-1361 (2007) Kasashima,K., J. Biol. Chem. 281 (47), 36401-36410 (2006)
NCBI	NP_001138303.1,NP_001254629.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Prohibitin-2,B-cell receptor-associated protein BAP37,D-prohibitin,Repressor of estrogen receptor activity,PHB2 {ECO:0000312\|EMBL:AAH147661,ECO:0000312\|HGNC:HGNC:30306}
Similar products	Prohibitin-2, D-prohibitin, B-cell receptor-associated protein BAP37, Repressor of estrogen receptor activity, PHB2 {ECO:0000312\|EMBL:AAH147661, ECO:0000312\|HGNC:HGNC:30306}
Available
Manufacturer - Category	Primary Antibodies; Signal Transduction; Mitochondrion; SARS-Human interactions
Manufacturer - Targets	This REA (PHB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human REA (PHB2).
Bio Background	PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB10629
Gene Name	PHB2 {ECO:0000312\|EMBL:AAH14766.1, ECO:0000312\|HGNC:HGNC:30306}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, C, M, Rat
Calculated Molecular Weight	33296
Antigen Source	HUMAN
Antigen Region	66-95
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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