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MGMT Antibody (C-term)

MGMT Antibody (C-term)

Item no.	ABC-AP7341b
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies Astrocytoma
Type	Antibody Polyclonal
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Kim,J.I., Suh,J.T. Hum. Pathol. 40 (7), 934-941 (2009) Chen,S.P., Chiu,S.C. Genet Test Mol Biomarkers 13 (1), 67-71 (2009) Slupphaug,G., Lettrem,I. Carcinogenesis 13 (10), 1769-1773 (1992) Lee,S.M., Crowther,D. Br. J. Cancer 66 (2), 331-336 (1992)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Methylated-DNA--protein-cysteine methyltransferase,6-O-methylguanine-DNA methyltransferase,MGMT,O-6-methylguanine-DNA-alkyltransferase,MGMT
Similar products	MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
Available
Manufacturer - Category	Crown Antibodies; Primary Antibodies
Manufacturer - Targets	This MGMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-182 amino acids from the C-terminal region of human MGMT.
Bio Background	MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. This protein repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the protein is irreversibly inactivated.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB19082
Gene Name	MGMT
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	21646
Antigen Source	HUMAN
Antigen Region	156-182
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 2/5/2026

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