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TEK (TIE2) Antibody (C-term)

TEK (TIE2) Antibody (C-term)

Item no.	ABC-AP7684A
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TEK, TIE2, VMCM, VMCM1, Angiopoietin-1 receptor, Endothelial tyrosine kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK, CD202b, hTIE2
Available
Primary Accession	Q02763
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Bio References	Cascone, I., et al., Blood 102(7):2482-2490 (2003). DeBusk, L.M., et al., Arthritis Rheum. 48(9):2461-2471 (2003). Poncet, S., et al., Neuropathol Appl Neurobiol 29(4):361-369 (2003). Lee, H.J., et al., Biochem. Biophys. Res. Commun. 304(2):399-404 (2003). Sussman, L.K., et al., Cancer Biol. Ther. 2(3):255-256 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB01525-01526
Gene ID	7010
Gene Name	TEK
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of TEK (arrow) using rabbit polyclonal TEK Antibody (C-term)(Cat.#AP7684a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TEK gene (Lane 2) (Origene Technologies).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Formalin-fixed and paraffin-embedded human testis tissue reacted with TEK Antibody (C-term) (Cat.#AP7684a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	Q06807
Predicted	B
Isotype	Rabbit Ig
Calculated MW	125830
Antigen Region	758-789
Antigen Source	HUMAN
Target/Specificity	This TEK (TIE2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2).
NCBI Accession	NP_000450.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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