Comparison

LOK Antibody (C-term E707)

Item no. ABC-AP7959b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, STK10, LOK
Available
Primary Accession
O94804
Antigen Type
Synthetic Peptide
Bio Background
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
Bio References
Kuramochi, S., et al., Immunogenetics 49(5):369-375 (1999).
Gene ID
6793
Gene Name
STK10
Reactivity
H
Calculated MW
112135
Antigen Region
692-721
Antigen Source
HUMAN
Target/Specificity
This LOK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human LOK.
NCBI Accession
NP_005981.3

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