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CYP7A1 Antibody (C-term)

CYP7A1 Antibody (C-term)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	ABC-AP7996A
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P22680
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.
Bio References	Lenicek, M., J. Lipid Res. 49 (12), 2664-2667 (2008) Nelson, D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Clonality	Polyclonal
Clone/Animal Names	RB17086
Gene ID	1581
Gene Name	CYP7A1 {ECO:0000303\|PubMed:12077124, ECO:0000312\|HGNC:HGNC:2651}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of CYP7A1 Antibody (C-term) (Cat.#AP7996a) in K562(lane 1), HepG2(lane 2) cell line lysates (35ug/lane). CYP7A1 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Anti-CYP7A1 Antibody (C-term) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Other Accession	P51542
Predicted	Rb
Isotype	Rabbit Ig
Calculated MW	57661
Antigen Region	476-504
Antigen Source	HUMAN
Target/Specificity	This CYP7A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human CYP7A1.
NCBI Accession	NP_000771.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-AP7996A-datasheet.pdf

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Amount: 400 ul

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Delivery expected until 7/4/2024