Comparison

ACR Antibody (C-term)

Item no. ABC-AP9079b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Acrosin, Acrosin light chain, Acrosin heavy chain, ACR, ACRS
Available
Primary Accession
P10323
Antigen Type
Synthetic Peptide
Bio Background
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Bio References
Dube, C., et.al., J. Androl. 26 (4), 519-528 (2005)
Furlong, L.I., et.al., Fertil. Steril. 83 (6), 1791-1796 (2005)
Gene ID
49
Gene Name
ACR
Reactivity
H
Calculated MW
45847
Antigen Region
387-416
Antigen Source
HUMAN
Target/Specificity
This ACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human ACR.
NCBI Accession
NP_001088.2

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