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IL-22 Receptor Antibody

IL-22 Receptor Antibody

Item no.	ABC-ASC10148
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Dumoutier L, Louahed J, Renauld JC. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J Immunol. 2000;164(4):1814-9. Dumoutier L, Van Roost E, Colau D, Renauld JC. Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc Natl Acad Sci USA. 2000 ;97(18):10144-9. Xie MH, Aggarwal S, Ho WH, et al. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem. 2000;275(40):31335-9. Kotenko SV, Izotova LS, Mirochnitchenko OV, et al. Identification of the functional interleukin-22 (IL-22) receptor complex: J Biol Chem. 2001;276(4):2725-32.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IL-22 Receptor Antibody: IL22R,CRF2-9,IL22R1,IL22R,Interleukin-22 receptor subunit alpha-1,Cytokine receptor class-II member 9,IL-22 receptor subunit alpha-1,interleukin 22 receptor,alpha 1
Similar products	IL22R, Interleukin-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, alpha 1, CRF2-9, IL22R1, IL-22 receptor subunit alpha-1, IL-22 Receptor Antibody: IL22R, interleukin 22 receptor
Available
Manufacturer - Category	Primary Antibodies; Immunology; Signal Transduction; Jak-STAT signaling KEGG
Manufacturer - Targets	IL22RA1;
Storage Conditions	IL-22 Receptor antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
Clonality	Polyclonal
Gene Name	IL22RA1
Reactivity	H, Rat
Calculated Molecular Weight	63077
Antigen Source	Homo sapiens
Purification	IL-22 Receptor Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 1 µg/mL. An approximately 62 kDa band can be detected.
Positive Control	HepG2 Cell Lysate
Buffer	IL-22 Receptor Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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