Prosapip1 Antibody

O60299

Prosapip1 Antibody: Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Polyclonal

LZTS3 (HGNC:30139)

Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 µg/mL.

Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 µg/mL.

Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 µg/mL.

NP_055546; 7662176

71791

ProSAPiP1;

Prosapip1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Prosapip1 antibody can be used for detection of Prosapip1 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.

Prosapip1 Antibody is supplied in PBS containing 0.02% sodium azide.