ZNF346 (CT) Antibody

Q9UL40

ZNF346 (CT) Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.

Polyclonal

ZNF346

Western blot analysis of ZNF346 in human kidney tissue lysate with ZNF346 antibody at (A) 1 and (B) 2 µg/mL.

Immunohistochemistry of ZNF346 (CT) in human kidney tissue with ZNF346 (CT) antibody at 5 µg/mL.

Immunofluorescence of ZNF346 in human kidney tissue with ZNF346 antibody at 20 µg/mL.

NP_036411; 6912440

32933

ZNF346; ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist; this antibody will recognize the two longest isoforms

ZNF346 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.

ZNF346 (CT) Antibody is supplied in PBS containing 0.02% sodium azide.