Comparison

L1TD1 Antibody

Item no. ABC-ASC11358
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Primary Accession
Q5T7N2
Application
WB, E
Bio Background
L1TD1 Antibody: L1TD1 (ECAT11) is a member of the family of Embryonic Stem Cell Associated Transcripts (ECAT) that play an important role in stem cell biology. ECAT4 (Nanog) is a master regulator for the maintenance of mESC and hESC. ECAT5 was identified to be Embryonic stem cell expressed Ras (ERas), a Ras-like oncogene that is important in regulating mESC proliferation. ECAT9 (GDF3) is an important factor that helps maintain mESC pluripotency by inhibiting bone morphogenetic protein (BMP) signaling. L1TD1 is highly enriched in undifferentiated hESC and L1TD1 is a target gene of Nanog.
Bio References
Iwabuchi KA, Yamakawa T, Sato Y, et al. ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency. PLoS One. 2011; 6:e20461.
Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113:631-42
Takahashi K, Mitsui K, Yamanaka S. Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature 2003; 423:541-5
Wong RC, Ibrahim A, Fong H, et al. L1TD1 is a marker for undifferentiated human embryonic stem cells. PLoS One 2011; 6:e19355.
Clonality
Polyclonal
Gene ID
54596
Gene Name
L1TD1
Reactivity
H
Legend image 1
Western blot analysis of L1TD1 in Jurkat cell lysate with L1TD1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Type image 1
WB
Other Accession
NP_061952; 157694505
Isotype
IgG
Calculated MW
98850
Antigen Source
Homo sapiens
Target/Specificity
L1TD1; L1TD1 antibody is predicted to not cross-react with other ECAT protein family members
Purification
L1TD1 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
L1TD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form
Liquid
Application Notes
L1TD1 antibody can be used for detection of L1TD1 by Western blot at 1 µg/mL.
Positive Control
Jurkat Cell Lysate;
Buffer
L1TD1 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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