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KLF12 Antibody (monoclonal) (M01)

KLF12 Antibody (monoclonal) (M01)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Clone	30000
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB
Amount	100 ug
Host	Mouse
Item no.	ABC-AT2630a
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	Q9Y4X4
Antigen Type	Recombinant Protein
Application	WB
Bio Background	Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Bio References	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Petersen GM, et al. Nat Genet, 2010 Mar. PMID 20101243.A functionally relevant IRF5 haplotype is associated with reduced risk to Wegener's granulomatosis. Wieczorek S, et al. J Mol Med, 2010 Apr. PMID 20049410.No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort. Eyre S, et al. Ann Rheum Dis, 2010 Jul. PMID 19907058.Kr?ppel-like factor 12 plays a significant role in poorly differentiated gastric cancer progression. Nakamura Y, et al. Int J Cancer, 2009 Oct 15. PMID 19588488.
Clonality	Monoclonal
Gene ID	11278
Gene Name	KLF12
Subtitle	Mouse monoclonal antibody raised against a partial recombinant KLF12.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	Western Blot analysis of KLF12 expression in transfected 293T cell line by KLF12 monoclonal antibody (M01), clone 3E4. Lane 1: KLF12 transfected lysate(44.2 KDa). Lane 2: Non-transfected lysate.
Type image 2	WB
Dilution image 2	1:500~1000
Other Accession	NM_007249
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	KLF12 (NP_009180, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_009180.3
	Clone: 30000
Org Accession	NP_009180
Gene Description	Kruppel-like factor 12
Gene Summary	Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

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Amount: 100 ug

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Delivery expected until 7/4/2024