Toll-Like Receptor 5 (TLR5) Antibody

Toll-Like Receptor 5 (TLR5)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

TLR5 Antibody is a Rabbit Polyclonal antibody against TLR5. This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009].

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

TLR5

Purified by affinity chromatography.