Comparison

Interleukin-6 (IL-6)

Item no. ANOG-MO-C40091B
Manufacturer Anogen
Amount 0.5mg
Category
Type Antibody Monoclonal
Format Aff. Pur
Applications WB, FC, ELISA
Clone 2E10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a kappa
Protein Family Cytokine, Growth Factors
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products IL-6
Available
Description
Mouse monoclonal antibody to human interleukin-6 (IL-6)
Target Protein
Human IL-6
Immunogen
Purified recombinant human IL-6
Specificity
Reactive with recombinant human IL-6
Purification
Protein G affinity purified
Species Reactivity
Human, other species not tested
Myeloma
F0
Background
IL-6, also called B-cell stimulatory factor-2 (BSF-2), is an important cytokine for the differentiation of B-cells into immunoglobulin-secreting cells. IL-6 is mainly produced by T-cells, macrophages and endothelial cells in response to pathogenic molecular stimuli during infection, trauma and the growth phase of some types of cancer. IL-6 is up-regulated by the binding of Toll-like receptors to antigen pattern ligands. In acute inflammatory phase, IL-6 causes increased body temperature by initiating synthesis of Prostaglandin E2 in hypothalamus.
Formulation
Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution
Double distillated water is recommended to reconstitute the antibody.
Application info
ELISA: The antibody reacts with recombinant IL-6 antigen.
Western blot: The antibody recognizes recombinant human IL-6 on blot. Fluorescence flow cytometry
Research Area
Cytokine, growth factor, inflammatory and autoimmune diseases
Storage
Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.5mg
Available: In stock
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