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Prostate Specific Membrane Antigen (PSMA)

Prostate Specific Membrane Antigen (PSMA)

Item no.	ANOG-MO-T40086A
Manufacturer	Anogen
Amount	0.5mg
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Heart & Blood Cancer Testicular & Prostate Cancer
Type	Antibody Monoclonal
Format	Aff. Pur
Applications	WB, IHC, ELISA
Clone	YPSMA-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b kappa
Protein Family	Tumor Marker
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	PSMA
Available
Description	Mouse monoclonal antibody to human Prostate Specific Membrane Antigen (PSMA)
Target Protein	Human Prostate Specific Membrane Antigen (PSMA)
Immunogen	Crude membrane protein preparation from pooled prostate malignant carcinoma from China.
Specificity	This antibody is reactive to PSMA expressed LNCap cell lines.
Purification	Protein G affinity purified
Species Reactivity	Human, others not tested
Cross Reactivity	Little or no cross-reactivity to benign prostate hyperplasia (BPH) or to normal prostatic tissue.
Myeloma	Sp2/0-Ag14
Background	Prostate specific membrane antigen (PSMA) is a type II trans-membrane glycoprotein found in the epithelium of prostate. It is also detectable in duodenal mucosa, renal tubules and some neuroendocrine cells. In other normal tissue, PSMA expression is not detectable. Because the expression of this membrane is elevated in malignant prostate tumour, PSMA has been used as a marker as well as a therapeutic target for prostate cancer. Elevated PSMA expression has also been identified in metastases of lymph nodes.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	Immuno-histochemistry: This antibody was used on formalin-fixed paraffin embedded and frozen tissue sections. Indirect ELISA: This antibody is reactive to PSMA expressing LNCap cells coated ELISA plate. Western blot:The antibody, when used at 1ug/ml concentration, identified the 100KDa PSMA in LNcap cell extract.
Research Area	Oncology
Storage	Store at -20C
Reference	"PSMA mimotope isolated from phage displayed peptide library can induce PSMA specific immune response" Cell Research (1999), 9, 271-280.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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