« Back
Home /
STAT3 Antibody (Ab-705)

STAT3 Antibody (Ab-705)

Item no.	AP50012
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IHC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	STAT3, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor
Available
Primary Accession	P40763
Antigen Type	Synthetic Peptide
Application	WB, IHC
Bio Background	Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Bio References	Akira S., et al.Cell 77:63-71(1994). Della Pietra L., et al.Gene 213:119-124(1998). Ota T., et al.Nat. Genet. 36:40-45(2004). Della Pietra L., et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases. Zhang X., et al.Science 267:1990-1994(1995).
Clonality	Polyclonal
Gene ID	6774
Gene Name	STAT3 (HGNC:11364)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of lysates from SK-N-MC, Hela cell line (from left to right), using STAT3 Antibody (Ab-705)(B7224). B7224 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using STAT3 (Ab-705) Antibody.
Type image 2	IHC
Dilution image 2	1:50-1:100

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

AP50012-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 12/4/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer