ITGAM Antibody - C-terminal region

Polyclonal Antibody

Wet Ice

Human

integrin subunit alpha M

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (' Mac-1' ), or inactivated-C3b (iC3b) receptor 3 (' CR3' ). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

NP_000623.2

Polyclonal

The immunogen is a synthetic peptide directed towards the C terminal region of human ITGAM