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CD5 (Mantle Cell Lymphoma Marker)(B-B8), CF647 conjugate, 0.1mg/mL

CD5 (Mantle Cell Lymphoma Marker)(B-B8), CF647 conjugate, 0.1mg/mL

Item no.	B-BNC470995-100
Manufacturer	Biotium
Amount	100 uL
Quantity options	100 uL 500 uL
Category	Oncology Antibodies Primary Antibodies By Organ Heart & Blood Cancer Lymphatic System Cancer
Type	Antibody Primary
Format	Liquid
Applications	FC, IF
Clone	B-B8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Conjugate/Tag	CF647
Citations	Inf Immunity (1996) 64(5): 1595-1599. (cell depletion) Br J Haematol (2013) 163: 182-193. (antibody internalization)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary
Manufacturer - Applications	Functional studies (published)\|Flow, surface (expected)\|IF (expected)
Manufacturer - Category	Antibodies
Manufacturer - Targets	CD5
Manufacturer - Conjugate / Tag	CF647
Manufacturer - Host	Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Shipping Temperature	Room temperature
Storage Conditions	Store at 2 to 8°C\|Protect fluorescent conjugates from light
Molecular Weight	67 kDa
Manufacturer - Research Area	Immunology
Description	This antibody recognizes a 67 kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.
Product origin	Animal
Ingredient of biological origin	Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Special handling for PI and label	Protect from light
Undated stability guarantee in PI	2 years
Stability at RT during shipping (protected from light)	Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity	41116161
UNSPSC Commodity Title	Primary and secondary antibodies for multiple methodology immunostaining detection application
Classified or regulated chemicals	0.05% sodium azide (CAS 26628-22-8)
Concentration	0.1 mg/mL
Storage buffer	PBS, 0.1% BSA, 0.05% azide
Dated shelf life printed on label	Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)	T cells activated with PHA
Clonality	Monoclonal
Regulatory Status	For research use only (RUO)
Human Gene Symbol	CD5
Unigene	58685
Positive Control	293T, Ramos, or MOLT-4 Cells. Tonsil.
Antibody target cellular localization	Plasma membrane
Cell tissue expression	Lymphocytes\|T-cells
Tumor expression	Leukemia/lymphoma
Antibody application notes	Not suitable for frozen tissues\|Flow cytometry: 0.5-1 ug/million cells\|Immunofluorescence: 0.5-1 ug/mL\|Optimal dilution for a specific application should be determined by user
Expected Antibody Applications	Flow (surface) (expected)\|Functional studies (published for clone)\|IF (expected)
Manufacturer - Antibody Reactivity	CD5

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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B-BNC470995-100-datasheet.pdf

B-BNC470995-100-safety-datasheet.pdf