CD11c(HC1/1), CF680R conjugate, 0.1mg/mL

Primary

Antibodies

CF680R

Room temperature

145 kDa

CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells. It induces cellular activation and helps trigger neutrophil respiratory burst. It is expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

2 years

41116161

0.05% sodium azide (CAS 26628-22-8)

PBS, 0.1% BSA, 0.05% azide

Human monocytic U937 phorbol ester-treated cells

For research use only (RUO)

248472

Plasma membrane

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL

CD11 antigen-like family member B|CD11b/CD18|CD49d|Cell surface glycoprotein MAC-1 subunit alpha|Complement Component Receptor 3 Alpha|CR3 Alpha Chain (CR3A)|Integrin alpha-M|Integrin beta 2 alpha subunit|ITGAM|Leukocyte adhesion receptor MO1, Ly-40|Mac-1a|MAC1|Mac1, alpha subunit|MAC1A|Macrophage antigen alpha polypeptide, MO1A|Neutrophil adherence receptor alpha M subunit