Item no. |
B-BNCB1746-500 |
Manufacturer |
Biotium
|
Amount |
500 uL |
Quantity options |
100 uL
500 uL
|
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Clone |
LN53 |
Specific against |
Virus |
Host |
Rat |
Isotype |
IgG2c |
Conjugate/Tag |
Biotin |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi's sarcoma associated herpes virus; KSHV |
Shipping condition |
Room temperature |
Available |
|
Specificity |
HHV8 |
Manufacturer - Type |
Primary |
Manufacturer - Category |
Antibodies |
Manufacturer - Targets |
Human Herpes Virus 8 |
Shipping Temperature |
Room temperature |
Storage Conditions |
Store at 2 to 8°C|Protect fluorescent conjugates from light |
Molecular Weight |
Not Known |
Description |
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
Product origin |
Animal |
Ingredient of biological origin |
Rat, BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells. |
Undated stability guarantee in PI |
2 years |
Stability at RT during shipping (protected from light) |
Stable at room temperature or 37°C (98°F) for 7 days. |
UNSPSC Commodity |
41116161 |
UNSPSC Commodity Title |
Primary and secondary antibodies for multiple methodology immunostaining detection application |
Classified or regulated chemicals |
0.05% sodium azide (CAS 26628-22-8) |
Concentration |
0.1 mg/mL |
Storage buffer |
PBS, 0.1% BSA, 0.05% azide |
Dated shelf life printed on label |
Guaranteed for at least 24 months from date of receipt when stored as recommended |
Immunogen (Secondaries, for anti tag only) |
Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 |
Clonality |
Monoclonal |
Regulatory Status |
For research use only (RUO) |
Human Gene Symbol |
Not Applicable |
Unigene |
Not Applicable |
Positive Control |
Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue. |
Tumor expression |
Leukemia/lymphoma|Sarcoma |
Antibody application notes |
For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry |
Antibody Number |
#1746 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.