Comparison

CD147(CB43), 0.2mg/mL

Item no. B-BNUB0363-500
Manufacturer Biotium
Amount 500 uL
Quantity options 100 uL 500 uL
Category
Type Antibody Primary
Format Liquid
Applications FC, IF
Clone RIV7
Specific against Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host Mouse
Isotype IgG2a Kappa
Conjugate/Tag BSA
Citations

  1. Knapp W. et al. (eds) Leukocyte Typing IV, p314-330, Oxford University Press, Oxford, 1989.
  2. Br J Haematol (2004) 128: 73-81. (functional studies)

ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; p55; T cell antigen T4/LEU3; T cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
Shipping Condition Room temperature
Available
Manufacturer - Type
Primary
Manufacturer - Applications
Functional studies (published)|Flow, surface (verified)|IF (verified)
Manufacturer - Category
Antibodies
Manufacturer - Targets
CD4
Manufacturer - Conjugate / Tag
Purified, with BSA
Manufacturer - Host
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Shipping Temperature
Room temperature
Storage Conditions
Store at 2 to 8°C|Protect fluorescent conjugates from light
Molecular Weight
55 kDa
Description
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product origin
Animal
Ingredient of biological origin
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Undated stability guarantee in PI
2 years
Stability at RT during shipping (protected from light)
Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity
41116161
UNSPSC Commodity Title
Primary and secondary antibodies for multiple methodology
immunostaining detection application
Classified or regulated chemicals
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Concentration
0.2 mg/mL
Storage buffer
PBS, 0.05% BSA, 0.05% azide
Dated shelf life printed on label
Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)
Human peripheral lymphocytes
Clonality
Monoclonal
Regulatory Status
For research use only (RUO)
Human Gene Symbol
CD4
Unigene
631659
Positive Control
Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.
Antibody target cellular localization
Plasma membrane
Cell tissue expression
Lymphocytes|Myeloid cells
Tumor expression
Leukemia/lymphoma
Antibody application notes
Functional studies: Order Ab without azide; Flow cytometry: 1-2 ug/million cells in 0.1 mL; Immunofluorescence: 1-2 ug/mL; Optimal dilution for a specific application should be determined.
Expected Antibody Applications
Functional studies (published for clone)
Manufacturer - Antibody Reactivity
CD4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 uL
Available: In stock
available

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