Comparison

IL3RA / CD123 (Acute Myeloid Leukemia Marker) (IL3RA/2065), 0.2mg/mL

Item no. B-BNUB2065-500
Manufacturer Biotium
Amount 500 uL
Quantity options 100 uL 500 uL
Category
Type Antibody Monoclonal
Format Liquid
Clone IL3RA/2065
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Conjugate/Tag BSA
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD123,hIL3Ra,IL-3R-alpha,IL-3RA,IL3RAX,IL3RAY,IL3RX,IL3RY,Interleukin-3 Receptor,alpha,Interleukin3 receptor,Interleukin3 receptor,Y-chromosomal
Shipping Condition Room temperature
Available
Manufacturer - Type
Primary
Manufacturer - Category
Primary Antibodies Only
Manufacturer - Targets
CD123|IL3RA
Manufacturer - Conjugate / Tag
Purified, with BSA
Manufacturer - Host
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Shipping Temperature
Room Temperature (Next day)
Storage Conditions
Store at 2 to 8°C|Protect fluorescent conjugates from light
Molecular Weight
70 kDa
Manufacturer - Research Area
Cytokines|Immunology|Inflammation
Description
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product origin
Animal
Ingredient of biological origin
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Undated stability guarantee in PI
2 years
Stability at RT during shipping (protected from light)
Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity
41116161
UNSPSC Commodity Title
Primary and secondary antibodies for multiple methodologyimmunostaining detection application
Classified or regulated chemicals
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Concentration
0.2 mg/mL
Storage buffer
PBS, 0.05% BSA, 0.05% azide
Dated shelf life printed on label
Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)
Recombinant human IL3RA protein fragment (around aa 26-171) (exact sequence is proprietary)
Clonality
Monoclonal
Regulatory Status
For research use only (RUO)
Human Gene Symbol
IL3RA
Unigene
632790
Positive Control
THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach
Antibody target cellular localization
Secreted (extracellular)
Validated in protein array
Monospecific
Antibody application notes
For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
Manufacturer - Antibody Reactivity
CD123|IL3RA
Antibody number
#2065

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 uL
Available: In stock
available

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