HER-2 / c-erbB-2 / neu / CD340(ERBB2/3257), 0.2mg/mL

Primary

Antibodies

Purified, with BSA

Store at 2 to 8°C|Protect fluorescent conjugates from light

Recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

2 years

41116161

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

PBS, 0.05% BSA, 0.05% azide

Recombinant human HER-2 protein fragment (around aa 311-462) (exact sequence is proprietary)

For research use only (RUO)

446352

Plasma membrane

Monospecific